For the integrated multidisciplinary approach to patient care

Return to the Southern Medical Journal

Current User S2 Access Level: -1 ()
CAN NOT ACCESS LEVEL 2
Letter to the Editor

Brucella melitensis in a Married Couple After a Trip Through Sicily

V Chanet, MD, F Gourdon, MD, O Baud, MD, J Beytout, PD, J P. Romaszko, MD
Volume: 98 Issue: 8 August, 2005

Abstract:

Brucellosis, which has dramatically decreased in France, remains a public health problem in Mediterranean countries. We report the case of a 59-year-old man who presented with isolated fever one month after returning from Italy. He related the consumption of local products in Sicily. Laboratory tests showed inflammation, thrombocytopenia, and cytolysis. The agglutination test for Brucella was positive. Serology forYersinia was negative. The patient was given a one-month course of tetracycline with improvement. One month later, he presented again with fever. On heart auscultation, a systolic murmur was noted. Laboratory findings showed platelets 158.109/L, sedimentation rate 17 mm/h, C-reactive protein 54 mg/dL, (normal range < 10 mg/dL), and cytolysis 2 (5 × normal range). Echocardiography showed aortic valve vegetation. A blood culture was positive for Brucella melitensis. The patient was prescribed ceftriaxone for four weeks, doxycycline and rifampicin for seven weeks, and made an uneventful recovery. His 50-year-old wife also presented with fever four months after their return. She, too had consumed local products in Sicily, but had a negative brucellosis serology when her husband's agglutination test revealed a positive finding. At this time, however, although the examination was normal, laboratory tests indicated inflammation and thrombocytopenia, and a blood culture identified B melitensis. Cardiac echocardiography was normal. She responded well to a one month course of cyclin.

Article:

This content is limited to qualifying members. Please click on an option below to view in full. Click here to compare all member plans.

Login

Silver/Gold members login for full access. Other members login to view purchase options.

Create a New Account

Create a new complimentary account/login to view purchase options.

Images:

This content is limited to qualifying members. Please click on an option below to view in full. Click here to compare all member plans.

Login

Silver/Gold members login for full access. Other members login to view purchase options.

Create a New Account

Create a new complimentary account/login to view purchase options.

References:

1. Picciotto D, Verso MG, Lacca G, et al. The epidemiological trend of brucellosisin the provinces of Sicily. Med Lav 1999;90:786– 790.
 
2. Castillo Dominguez JC, Anguita Sanchez M, Ramirez Moreno A, et al. Abscess of the mitral- aortic confluence and perforation of the mitral valve in a patient with Brucella endocarditis. Rev Esp Cardiol1998;51:1002–1005.
 
3. Hadjinikolaou L, Triposkiadis F, Zairis M, et al. Successful management of Brucella mellitensis endocarditis with combined medical and surgical approach. Eur J Cardiothorac Surg 2001;19:806–810.
 
4. Cohen N, Golik A, Alon I, et al. Conservative treatment for Brucella endocarditis. Clin Cardiol1997;20:291–294.
 
5. Alsoub H. Brucella infective endocarditis: a report of four successfully treated patients. Clin Microbiol Infect 2001;7:382–385.
 

CME:

Portions of this issue may be available for CME credit. Please email education@sma.org for a complete listing of current Southern Medical Journal activities, as well as other SMA educational offerings.

This content is limited to qualifying members. Please click on an option below to view in full. Click here to compare all member plans.

Login

Silver/Gold members login for full access. Other members login to view purchase options.

Create a New Account

Create a new complimentary account/login to view purchase options.

This content is limited to qualifying members. Please click on an option below to view in full. Click here to compare all member plans.

Login

Silver/Gold members login for full access. Other members login to view purchase options.

Create a New Account

Create a new complimentary account/login to view purchase options.

Permissions