Original Article

Efficacy and Safety of Nonvitamin K Oral Anticoagulants following Cardiac Valve Replacement

Objective: To compare the efficacy and safety of nonvitamin K oral anticoagulants (NOACs) and vitamin K antagonists (VKAs) following bioprosthetic cardiac valve replacement. Methods: This was a retrospective analysis conducted at a community teaching hospital in the southeastern United States between August 2015 and August 2018. Patients 18 years of…

Posted in: bleeding 6 thromboembolism 6

Original Article

Transfusion Requirements in ESRD Patients Admitted with GI Hemorrhage Undergoing Inpatient Endoscopy

Objectives: To date there are no studies evaluating the utilization of blood products in patients with end-stage renal disease (ESRD) with gastrointestinal (GI) hemorrhage. This study estimated transfusion needs and determined predictors available at the time of admission for patients with ESRD admitted to a university hospital with GI bleeding…

Posted in: bleeding 6 end-stage renal disease 5 gastrointestinal 5 hemorrhage 7 transfusion 5

Case Report

Successful Treatment of Severe Gastrointestinal Bleeding Secondary to Crohn Disease with Recombinant Factor VIIa

A 58-year-old man diagnosed with ileocolonic Crohn disease was admitted to the emergency room with massive lower gastrointestinal hemorrhage and hypovolemic shock. Treatment was started with methylprednisolone, metronidazole and omeprazole. Within the next 24 hours, he received a total of 9 U of red blood cell concentrate and 2 U…

Posted in: bleeding 6 Crohn disease 5 hemorrhage 7 recombinant factor VIIa 2 surgery 23

Review Article

Easy Bruisability

Abstract:Physicians often see patients who complain of “easy bruising.” The skill of the clinician is to identify those patients likely to have a potentially serious underlying disorder from those who do not. A detailed history often provides sufficient information. A comprehensive physical examination and possibly some baseline laboratory studies can…

Posted in: bleeding 6 review 2

Review Article

Preventing Warfarin-related Bleeding

Warfarin is one of the most common anticoagulants in current use. It maintains a narrow therapeutic index resulting in a significant amount of bleeding. Changes in concomitant medication use and acute illnesses are common causes of overanticoagulation. Monitoring regimens based on patient characteristics and the intensity and duration of anticoagulant…

Posted in: anticoagulation 12 bleeding 6 Warfarin 10

Original Article

Thoracic Packing for Uncontrolled Bleeding in Penetrating Thoracic Injuries

We present a series of three patients who suffered penetrating thoracic injury, and in whom thoracic packing was used as a life-saving procedure. Survival among these patients paralleled the severity and extent of the original injuries. Restriction of cardiac filling and lung expansion are potential deterrents from using this technique;…

Posted in: bleeding 6 packing 2 trauma 24
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