Original Article

Measuring Adherence to Hepatitis C Direct-Acting Antiviral Medications: Using the VAS in an HCV Treatment Clinic

Objectives: To implement the widespread treatment of hepatitis C virus (HCV), validated self-report measures to assess medication adherence are needed for monitoring patients who are prescribed HCV direct-acting antivirals (DAAs). The Visual Analog Scale (VAS) is an efficient and well-validated tool for measuring adherence to antiretrovirals in human immunodeficiency virus…

Posted in: adherence 10 chronic hepatitis C 3 infectious diseases 2

Case Report

Simultaneous Occurrence of Pleural Effusion and Interstitial Pneumonitis After Treatment with Pegylated Interferon for Hepatitis C Virus Infection

Combination of pegylated interferon and ribavirin has been the standard program for hepatitis C virus (HCV) infection. Pulmonary complications, although uncommon, have been reported in association with the use of interferon, and pleural effusion is rare. We report the second case of pleural effusion and interstitial pneumonitis in a patient…

Posted in: chronic hepatitis C 3 pegylated interferon 2 pleural effusion 9 pulmonary toxicity 3

Case Report

Severe Stomatitis Complicating Treatment With Pegylated-Interferon α-2a and Ribavirin in an HCV-Infected Patient

Objective:To report a case of severe stomatitis probably induced by peginterferon α-2a. Methods and Results:A 42-year-old man with chronic hepatitis C genotype 1b commenced treatment with peginterferon α-2a 180 &mgr;g subcutaneously weekly and ribavirin 1000 mg/d orally. Twenty-eight days after commencing treatment, the patient experienced difficulties with swallowing, dryness of…

Posted in: adverse drug reaction 6 chronic hepatitis C 3
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