Review Article

Therapeutic Approach to Heart Failure Management: Insight from Clinical Trials

Heart failure (HF) is a global burden and, irrespective of age, sex, race, nationality, and geography, affects individuals across the world. Several reports mentioned that, globally, more than 64 million people, which accounts for 1% to 3% of the total global population, are living with HF. In the United States,…

Posted in: clinical trials 4 Congestive Heart Failure 12 renin-angiotensin-aldosterone system (RAAS) 2

Original Article

Regional Variation in HIV Clinical Trials Participation in the United States

Objectives: To ensure generalizability of clinical research results, it is important to enroll a heterogeneous population that is representative of the target clinical population. Earlier studies have found regional variation in participation in human immunodeficiency virus (HIV) clinical trials, with the lowest rates seen in the southern United States. Rates…

Posted in: clinical trials 4 HIV 30 United States 3

CME Topic

Clinical Definition of COPD Exacerbations and Classification of Their Severity

Abstract:A standardized definition of chronic obstructive pulmonary disease (COPD) exacerbation still represents an unmet need in respiratory medicine; definitions currently rely on clinical empiricism with little evidence-based scientific support. Exacerbations of COPD are certainly clear events in the mind of practicing physicians. However, when one tries to provide simple concepts…

Posted in: clinical trials 4 COPD 10

Original Article

A Descriptive Analysis of Authorship Within Medical Journals, 1995–2005

Introduction: The emphasis on publications for promotion in academic medicine would lead one to the theory that authorship numbers would increase proportionally with this emphasis. To investigate authorship trends across a number of periodicals, we performed a descriptive study comparing two full years of published articles spaced ten years apart…

Posted in: clinical trials 4
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