Original Article

Hepatic Dysfunction in Patients Receiving Intravenous Amiodarone

Objectives: Amiodarone is a commonly used antiarrhythmic drug. Hepatotoxicity following chronic oral administration occurs in 1% to 3% of patients. Hepatotoxicity following intravenous (IV) administration is infrequent but may be associated with dramatic increases in serum transaminases. We describe the incidence of liver toxicity among patients receiving IV amiodarone during…

Posted in: amiodarone 5 arrhythmia 2 Atrial Fibrillation 13 hepatotoxicity 3 intravenous 3 mortality 38

Review Article

Nitrofurantoin-Induced Hepatotoxicity: A Rare Yet Serious Complication

Nitrofurantoin is a commonly prescribed antibiotic for thetreatment of recurrent uncomplicated urinary tract infections. Its importance has been emphasized by the current international clinical practice guidelines for the management of uncomplicated cystitis. Since its introduction into clinical practice, nitrofurantoin has been associated with various adverse effects, including hepatotoxicity. We searched…

Posted in: drug induced liver injury 2 hepatotoxicity 3

Case Report

Acute Liver Failure Due to Iron Overdose in an Adult

The vast majority of acute iron toxicity cases occur in children less than 5 years of age. Moreover, clinical hepatic injury is uncommon with most symptoms stemming from the intestinal tract (eg, nausea, vomiting, diarrhea). Therefore, physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with…

Posted in: hepatotoxicity 3
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