Review Article

A Brief Review of the Pharmacology of Hyperkalemia: Causes and Treatment

Hyperkalemia is a common problem in both inpatients and outpatients. Many disease states (eg, chronic kidney disease) and medications may precipitate hyperkalemia. There are several drugs now available to treat hyperkalemia. Many of these drugs are relatively new. This review provides information regarding drug-induced causes of hyperkalemia and provides detailed…

Posted in: calcium 3 hyperkalemia 3

Original Article

Intestinal Necrosis due to Sodium Polystyrene Sulfonate (Kayexalate) in Sorbitol

Background:Sodium polystyrene sulfonate (SPS, Kayexalate) has been implicated in the development of intestinal necrosis. Sorbitol, added as a cathartic agent, may be primarily responsible. Previous studies have documented bowel necrosis primarily in postoperative, dialysis, and transplant patients. We sought to identify additional clinical characteristics among patients with probable SPS-induced intestinal…

Posted in: hyperkalemia 3 ischemic colitis 4

Case Report

Extreme Hyperkalemia

Hyperkalemia is a potentially fatal condition and is defined by a serum potassium level (K+) of greater than 5.5 mmol/L. The associated prevalence of cardiac arrhythmia increases directly with the degree of hyperkalemia. The danger in the majority of hyperkalemia cases is cardiac dysrhythmia, and often ventricular fibrillation or asystole…

Posted in: hyperkalemia 3
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