Original Article

Analysis of a Guideline-Derived Resident Educational Program on Inpatient Glycemic Control

Objectives: To determine the effects of a guideline-derived resident educational program on inpatient glycemic control and length of hospital stay (LOS). Methods: We compared the following variables before and after resident education: percentage of patients on basal-plus-bolus regimens, mean fingerstick glucose (FSG), LOS, and rates of hypoglycemia (FSG

Posted in: hyperglycemia 8 hypoglycemia 7 insulin 8 length of stay 14

Original Article

Retrospective Chart Review of Children With Type 2 Diabetes Mellitus Evaluating the Efficacy of Metformin vs. Insulin vs. Combination Insulin/Metformin

Objectives: Type 2 diabetes mellitus is a growing problem in pediatrics and there is no consensus on the best treatment. We conducted this chart review on newly diagnosed pediatric patients with type 2 diabetes mellitus to compare the effect of treatment regimen on body mass index (BMI) and hemoglobin A1c…

Posted in: hemoglobin A1c 5 insulin 8 metformin 5 Obesity 70 pediatrics 33 type 2 diabetes mellitus 13

Review Article

Nonalcoholic Steatohepatitis: A Review of the Literature and Updates in Management

Nonalcoholic steatohepatitis is a common cause of liver inflammation and is associated with obesity, insulin resistance, and hyperlipidemia. There are concerns that it may turn out to be the most common cause of liver failure as prevalence of obesity increases. It leads to increased morbidity and mortality. Other causes of…

Posted in: fatty liver disease 2 insulin 8 necrosis 2 resistance 3 tumor 6

Review Article

The Continuation of Oral Medications with the Initiation of Insulin Therapy in Type 2 Diabetes: A Review of the Evidence

The combination of oral medications with insulin is inevitable in the treatment of type 2 diabetes. Unfortunately, there are no consensus statements available to guide the continuation or discontinuation of specific therapies. The clinician treating the type 2 diabetic patient must be aware of the literature regarding use of oral…

Posted in: insulin 8 type 2 diabetes 7

Review Article

Treating the Whole Patient for Optimal Management of Type 2 Diabetes: Considerations for Insulin Therapy

Primary care physicians are responsible for providing healthcare to most patients with type 2 diabetes. In this role, it is critical that physicians utilize a whole-patient treatment approach that includes lifestyle modifications and pharmacotherapy aimed to achieve glycemic control, in addition to the management of any comorbid conditions or risk…

Posted in: combination therapy 6 diabetes management 2 insulin 8

Review Article

Physiological and Behavioral Aspects of Glycemic Control and Hypoglycemia in Diabetes

Abstract:Homeostatic mechanisms that maintain blood glucose concentration within a narrow physiologic range are complex and redundant. Elaborate feedback loops involving insulin, glucagon, sympathoadrenal mediators, growth hormone, amylin, and incretins normally operate synchronously to keep blood glucose within a narrow set point. Individuals with diabetes have defects in glucose homeostatic pathways,…

Posted in: behavior 6 Diabetes 23 hypoglycemia 7 insulin 8

Review Article

Management of Diabetes-related Hypoglycemia

Iatrogenic hypoglycemia is the main factor limiting aggressive and optimal diabetes management. Rather than being an inevitable consequence of optimal glycemic control, however, hypoglycemia is avoidable and generally straightforward to manage when it occurs. Professional caregivers, patients, and their families are often fearful of hypoglycemia, even though most episodes are…

Posted in: Diabetes 23 hypoglycemia 7 insulin 8 primary care 64

Expired CME Article

Insulin Resistance in Polycystic Ovarian Disease

The classic polycystic ovarian syndrome (PCOS) was originally described by Stein and Leventhal as the association of amenorrhea with polycystic ovaries and, variably, hirsutism and/or obesity. It is estimated that 5 to 10% of women of reproductive age have PCOS. Although insulin resistance is not part of the diagnostic criteria…

Posted in: insulin 8 resistance 3 thiazolidinediones 2
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