Objective: Prior studies of the effect of father’s age on the risk of low birth weight (LBW, infant weight < 2500 g) have been inconclusive. In addition, previous investigators have not conducted a detailed analysis to determine whether paternal age (PA) interacts with maternal age (MA) on the outcome of...
Warfarin is the most widely used oral anticoagulant and is indicated for many clinical conditions. Levofloxacin, a fluoroquinolone, is one of the most commonly prescribed antibiotics in clinical practice and is effective against Gram-positive, Gram-negative, and atypical bacteria. While small prospective studies have not revealed any significant drug-drug interaction between…
Omeprazole is a commonly prescribed inhibitor of the gastric proton pump and has numerous indications in the treatment of gastrointestinal diseases. It is primarily metabolized through the CYP2C19 enzyme, a member of the P450 mixed-function oxidase group, although a minor pathway of metabolism is through CYP3A4, another P450 enzyme. Digoxin…
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