Original Article

Should Increased Levels of Urinary 8-Hydroxydeoxyguanosine in Chronic Gastritis Imply Intestinal Metaplasia or Gastric Atrophy?

Objectives: Helicobacter pylori (H pylori) infection induces chronic inflammation that can progress to gastric atrophy, intestinal metaplasia, and gastric adenocarcinoma. We have examined oxidative damage caused by Helicobacter pylori, metaplasia, and atrophy of gastric mucosal cells in patients with chronic gastritis by measuring their urinary 8-hydroxydeoxyguanosine (8-OHdG) levels. Methods: We…

Posted in: Helicobacter pylori 10 intestinal metaplasia 2

Case Report

H. pylori-Associated Gastric Cancer in a Husband-Wife Pair: A Veritable Family Affair

Abstract:Family environment probably represents a high route of transmission for H. pylori, a bacterium associated with gastric cancer (GC). We report two cases of GC in a husband-wife pair of immigrants from Romania. The disease was first diagnosed in the wife, and three years later in her husband of 55…

Posted in: gastric cancer 4 gastritis 2 intestinal metaplasia 2
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