Objectives: Remdesivir is a nucleotide analog used to treat coronavirus disease 2019 (COVID-19). We determined whether reduced kidney function is associated with the completion of a full course of remdesivir in hospitalized patients with COVID-19. Methods: This was a retrospective study of 1103 adults hospitalized with COVID-19. The primary outcome…
Approximately 158,500 adults and adolescents in the United States live with undiagnosed human immunodeficiency virus (HIV). Missed or delayed diagnoses adversely affect disease management and outcomes. This is particularly salient for patients receiving immunosuppressive and immunomodulatory therapy for the management of chronic inflammatory conditions, in which additional immunosuppression may increase…
Objectives: Endothelial dysfunction (ED) has been reported in patients with autosomal-dominant polycystic kidney disease (ADPKD). Coronary flow velocity reserve (CFVR) is a noninvasive test showing endothelial function of epicardial coronary arteries and coronary microcirculatory function. The aim of this study was to investigate the effect of the angiotensin receptor blocker,…
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