SMJ articles in the category "multiple myeloma"

Acknowledgment

Echocardiography-Defined Pulmonary Hypertension in Multiple Myeloma: Risk Factors and Impact on Outcomes

Objectives: Survival of patients with multiple myeloma (MM) has improved as a result of therapeutic advances. There is evidence that some patients with MM develop pulmonary hypertension (PH). The objective of this study was to identify risk factors of echocardiographic PH and its impact on outcomes of patients with MM….

Posted in: multiple myeloma 10 pulmonary hypertension 12

Case Report

Simultaneous Acute Myeloid Leukemia and Multiple Myeloma Successfully Treated with Allogeneic Stem Cell Transplantation

We present a case of concurrent diagnosis of acute myeloid leukemia (AML) with multiple myeloma with complex karyotype, which was successfully treated with allogeneic stem cell transplantation. A 51-year-old man with no past medical history presented with fatigue and anemia with blasts on peripheral smear. Bone marrow biopsy confirmed the…

Posted in: acute myeloid leukemia 2 multiple myeloma 10

Case Report

A Solitary Pelvic Extramedullary Plasmacytoma

A case of an extramedullary plasmacytoma (EMP), which presented with a solitary pelvic tumor, is reported. Complete tumor resection was performed, followed by radiation therapy. Our experience demonstrates a satisfactory short-term oncological outcome.

Posted in: multiple myeloma 10 plasmacytoma 3 radiation 4

Case Report

Plasma Cell Leukemia Presenting as Organizing Pneumonia Refractory to High-Dose Steroid Therapy

A case of steroid-refractory organizing pneumonia (OP) as the initial presentation of plasma cell leukemia (PCL) in a patient who had no prior exposure to chemotherapy or radiation is described. Since OP is traditionally a steroid-responsive disease, this case raises the possibility of a previously unknown patient subgroup with variable…

Posted in: multiple myeloma 10 organizing pneumonia 2 plasma cell leukemia 2

Case Report

Multiple Myeloma Presenting as Recurrent Sinopulmonary Infections

Multiple myeloma is a plasma cell malignancy that classically presents with bone pain secondary to osteolytic lesions, anemia, and renal insufficiency. A 49-year-old man presented for workup of possible primary immunodeficiency due to a history of recurrent sinopulmonary infection and abnormal immunoglobulin levels. He was subsequently diagnosed with multiple myeloma,…

Posted in: multiple myeloma 10

Case Report

Gastroduodenal Plasmacytoma Presenting with Jaundice

The duodenum and gastrointestinal tract are rarely involved by multiple myeloma, either diffusely or as a focal mass. A 59-year-old man was diagnosed with multiple myeloma and given chemotherapy. Four months later, he developed jaundice. Gastroduodenal plasmacytoma causing extrahepatic biliary obstruction was diagnosed. To the best of our knowledge, this…

Posted in: duodenum 4 multiple myeloma 10 plasmacytoma 3

Case Report

A Bone to Pick About Chest Pain

Abstract:Chest pain is an extremely common presenting symptom that is usually related to a cardiac cause. This case illustrates an unusual presentation of multiple myeloma as a cause of atypical chest pain. This case presentation shows the importance of having a broad differential diagnosis while evaluating patients with atypical chest…

Posted in: multiple myeloma 10

Case Report

Primary Plasma Cell Leukemia Presented as Progressive Paraplegia: A Case Report

Abstract:Plasma cell leukemia (PCL) is a rare plasma cell disorder. It is the leukemic variant of multiple myeloma. A 52-year-old man with an atypical presentation of primary plasma cell leukemia is reported. The patient presented with paraparesis which progressively worsened to paraplegia. MRI of the spine showed an extradural mass…

Posted in: multiple myeloma 10 plasma cell leukemia 2

Case Report

Giant Cell Arteritis Mimicking Multiple Myeloma; Diagnosed by PET Scan

This case report describes a patient who presented with severe anemia, monoclonal gammopathy, a high erythrocyte sedimentation rate and significant weight loss. These features were highly suggestive of multiple myeloma. Bone marrow aspiration was negative for myeloma on two occasions. A positron emission tomography (PET) scan showed extensive 2-flourodeoxy-glucose uptake…

Posted in: anemia 11 giant cell arteritis 3 multiple myeloma 10

Case Report

Thalidomide-induced Organizing Pneumonia

Twenty medications are associated with drug-induced organizing pneumonia; however, thalidomide is not listed as a potential causative agent. Thalidomide (Thalomid, Celgene Corp., Summit, NJ), an angiogenesis inhibitor and immunomodulator that reduces tumor necrosis factor-alpha, is used for the treatment of multiple myeloma. We report a case of organizing pneumonia in…

Posted in: multiple myeloma 10 organizing pneumonia 2 pulmonary toxicity 3 thalidomide 2
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