Objective: This single-center retrospective review examines the unique characteristics of young patients (ages 18 to 40 years) who were diagnosed as having non-small-cell lung cancer (NSCLC) at Markey Cancer Center, the only National Cancer Institute–designated cancer center in the state of Kentucky. Methods: This retrospective study examines adult patients with…
Objectives: Targeted therapies for non-small-cell lung cancers (NSCLCs) are based on the presence of driver mutations such as epidermal growth factor receptor (EGFR) and the echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) translocation. Endobronchial ultrasound-guided-transbronchial needle aspiration (EBUS-TBNA) is a first-line modality for diagnosing and staging NSCLC. A quality improvement…
Objectives: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the primary method for the diagnosis and staging of lung cancer. The purpose of this study was to assess the yield of EBUS-TBNA in the subtyping and genotyping of lung adenocarcinoma. Methods: Sixty-nine patients at Indiana University Hospital and Sidney and Lois…
Objective: The purpose of this study was to investigate the morbidity and mortality of 100 consecutive patients with pneumonectomy for non–small cell lung cancer at the University of Kentucky. Methods: We retrospectively reviewed the medical records of 100 consecutive pneumonectomy patients, 1998–2009. Results: The median age of patients was 59…
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