Multidisciplinary Clinical Case Study

Uremic Pericarditis: Distinguishing Features in a Now-Uncommon Clinical Syndrome

We present the case of a 47-year-old man with a history of diabetes mellitus and diabetic nephropathy who was admitted to our hospital with acute uremic myopericarditis. Echocardiography demonstrated a fibrinous pericardial effusion. The patient was initiated on hemodialysis for hyperkalemia, metabolic acidosis, and uremia. He subsequently developed shock from…

Posted in: cardiac tamponade 7 end-stage renal disease 5 pericardial effusion 4

Review Article

Protective Effect of Pulmonary Hypertension Against Right-Sided Tamponade in Pericardial Effusion

Patients with pericardial effusion are susceptible to cardiac tamponade. A compressing circumferential pericardial effusion typically results in an equalization of intracardiac and pericardial pressure during diastole and a progressive collapse of the right atrium and ventricle. Pulmonary hypertension that increases the afterload of the right ventricle may result in elevated…

Posted in: pericardial effusion 4 pulmonary hypertension 12 tamponade 2

Case Report

Pericardial Involvement as a Rare Manifestation of Hypereosinophilic Syndrome

Abstract:A 56-year-old female with idiopathic hypereosinophilic syndrome who presented with chest tightness, dyspnea and new-onset atrial fibrillation is reported. Work up revealed significant peripheral eosinophilia, pericarditis, and a pericardial effusion with tamponade physiology. Pericardiocentesis revealed predominant eosinophils (88%) in the pericardial fluid. After initial stabilization, pericardial effusion reaccumulated with persistence…

Posted in: eosinophilia 4 pericardial effusion 4 pericarditis 6

Original Article

Poor Outcomes Associated with Drainage of Pericardial Effusions in Patients with Pulmonary Arterial Hypertension

Objectives: Pulmonary arterial hypertension (PAH) in its advanced stages is complicated by right heart failure and often pericardial effusion. The optimal treatment of large or hemodynamically significant pericardial effusions in this group has not been defined. Methods: All patients followed at the Johns Hopkins Hospital for PAH during a 1-year…

Posted in: pericardial effusion 4 pulmonary arterial hypertension 5
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