Review Article

OPEN: Immune Checkpoint Inhibitor-Related Pulmonary Toxicity: A Comprehensive Review, Part II

The development of immune checkpoint inhibitors (ICIs) has changed the treatment paradigm for cancer. The ICIs nivolumab, pembrolizumab, and cemiplimab target programmed cell death protein 1, and durvalumab, avelumab, and atezolizumab target programmed death ligand 1. Ipilimumab targets cytotoxic T lymphocyte–associated antigen-4. Used as monotherapy or in combination, they have…

Posted in: pembrolizumab 2 pneumonitis 2

Case Report

Radiation Pneumonitis Successfully Treated with Inhaled Corticosteroids

Radiation pneumonitis is a well-described complication of chest radiotherapy administered to patients for mediastinal, breast, and lung tumors. Dyspnea, cough, and radiographic infiltrates within the field of radiation are typical symptoms and findings. Systemic corticosteroids are the traditionally accepted treatment, often with good clinical responses reported in a large number…

Posted in: corticosteroids 7 pneumonitis 2 radiation 4
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