Objective: There is a relation between tumor stage and grade with the risk of cancer recurrence in patients undergoing surgical treatment for kidney cancer. The association of patient comorbidity with disease recurrence is less well characterized. The objective of this study was to explore the association between comorbidity and the…
Abstract:The coexistence of multiple and synchronous primary neoplasms in the genitourinary system has rarely been described in the literature. To our knowledge, this is the first report of a very rare tumor, a “tubulocystic carcinoma,” simultaneously occurring with micropapillary urothelial carcinoma in the bladder and clear cell type renal cell…
A 21-year-old female with linear, flesh-colored papules on her face was diagnosed with cutaneous piloleiomyoma. Important associations for physicians to be aware of include uterine leiomyomas, leiomyosarcomas, and renal cell carcinoma. Mutations for this syndrome have been mapped to the fumarate hydratase gene.
A 64-year-old female patient presented with acute cerebellar ataxia. After ruling out vascular, infectious, metastatic, demyelinating, and medication etiologies, a paraneoplastic origin for her illness was determined. A renal mass was discovered and found to be renal cell carcinoma. Her symptoms resolved after a radical nephrectomy. Physicians should consider the…
Since its FDA approval in December 2005, sorafenib (Nexavar®) has been in use for the treatment of metastatic renal cell carcinoma. With this increased use have come reports of adverse effects of sorafenib. To the best of the authors’ knowledge, they are the first to describe an 80-year-old Asian male…
This report describes a patient with metastatic kidney cancer who developed a deep yellow skin discoloration while on therapy with the oral multitargeted tyrosine kinase inhibitor (TKI), sorafenib. A significant hand-foot syndrome, featuring acral skin desquamation and tender erythema at pressure points, was also present. A thorough clinicolaboratory investigation did…
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