Case Report

Severe Stomatitis Complicating Treatment With Pegylated-Interferon α-2a and Ribavirin in an HCV-Infected Patient

Objective:To report a case of severe stomatitis probably induced by peginterferon α-2a. Methods and Results:A 42-year-old man with chronic hepatitis C genotype 1b commenced treatment with peginterferon α-2a 180 &mgr;g subcutaneously weekly and ribavirin 1000 mg/d orally. Twenty-eight days after commencing treatment, the patient experienced difficulties with swallowing, dryness of…