Review Article

Dose-Response Relationships of Sulfonylureas: Will Doubling the Dose Double the Response?

type 2 diabetes mellitus is currently a global health problem. Although the armamentarium of oral hypoglycemic agents is continuously expanding, sulfonylureas (SUs) are still extensively used for the management of type 2 diabetes mellitus. However, despite decades of use, there is controversy as to the dosing of SUs. Despite many…

Posted in: sulfonylureas 2 type 2 diabetes mellitus 13

Review Article

Achieving Glycemic Control in Type 2 Diabetes: A Practical Guide for Clinicians on Oral Hypoglycemics

Type 2 diabetes mellitus has reached epidemic proportions in the United States. Cardiovascular morbidity and mortality are particularly high in this patient population. Improved glucose control, especially early in the course of diabetes, can slow or prevent complications, preserve β-cell function, and improve long-term outcomes. Within the last decade, new…

Posted in: metformin 5 sulfonylureas 2 thiazolidinediones 2 type 2 diabetes mellitus 13
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