Goals and Objectives

Southern Medical Journal is an interdisciplinary, multi-specialty Journal, and articles span the spectrum of medical topics, providing timely, up-to-date information for primary care physicians and specialists alike. The SMJ enables physicians to provide the best possible care to patients in this age of rapidly changing modern medicine.  Therefore, the readers of the SMJ are an appropriate target for this article.

Technological advances made possible through next-generation sequencing-based tests have led to a broad approach to testing for multiple genes simultaneously (called multigene panel testing), including those for which the patient does not meet clinical testing criteria. The increasing use of multigene panel tests has led to the identification of tumor protein p53 mutations among individuals without a family history that is characteristic of Li-Fraumeni syndrome. The study characterizes the clinical phenotype and follow-up care in a registry-based sample of women with pathogenic or likely pathogenic variants in the tumor protein p53 gene detected through multigene panel testing. Upon completion, the learner should be able to:

  • Understand the broad approach to multiple gene panel testing in certain forms of breast cancer;
  • Understand the impact of identifying genetic variants on cancer risk management recommendations

Course Information

CME Release Date: October 3rd, 2017
Valid for credit through:  October 3rd, 2018
Course type:  CME Journal Article
Sponsored in part by:  SMA Services, Inc.
Estimated time of completion: 1 hour


Credits Available

Southern Medical Association is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Southern Medical Association designates this CME Journal Article for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.  All healthcare professionals who are not MDs or DOs will receive a certificate of participation.


Instructions for Participation and Credit

This activity is designed to be completed within the time designated; learners should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period noted, following these steps:

  • Read the goals and objectives, accreditation information, and author disclosures.
  • Study the educational content and references.
  • Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score of 80%.
  • Complete the activity evaluation and attestation.

Upon completion of the evaluation and attestation, your certificate will be processed and emailed within 2 weeks.  Credits will be archived for 6 years; at any point within this time period you can contact Southern Medical Association for a duplicate copy of your credit.

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