Target Audience

This activity is designed for healthcare professionals including physicians, physician assistants, nurse practitioners, and allied healthcare professionals of all specialties.

Goals and Objectives

Introduction of new drugs in the standard of care continues at a significant rate. Some of these discoveries represent the identification of ways to manipulate novel pathways in disease states. The time lag between discovery and eventual implementation may be significant. One such barrier is a reluctance of prescribers to implement new modalities of care in complex health systems. One example of such “game changing” therapies is use of the neprolysin inhibitors in heart failure.

Heart failure is the leading cause of initial hospitalization and re-hospitalization within 30 days of discharge in those over 65 years of age. While the treatment of heart failure with reduced ejection fraction (HFrEF) remains evidence-based from clinical outcome trials, clinicians fail to use these strategies to keep patients from hospitalization and CV death. This lecture will address this practice gap using patient vignettes to suggest how best to treat patients with heart failure. In addition, the concept of heart failure with preserved ejection fraction (HFpEF) will be discussed, where the evidence base for improvement in outcome is currently lacking and treatment is based on symptomatic improvement. At the conclusion of the session, learners should be better prepared to:

  • Recognize examples of new drug therapies that have changed management in the last two years;
  • Describe the basic and Clinical Pharmacology of these new drug classes;
  • Implement these new therapies in every day practice.

Course Information

CME Release Date:  December 03, 2018
Valid for credit through:  December 03, 2019
Course type:  Video lecture

Credits Available

Southern Medical Association is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA PRA Category 1 Credits™

Southern Medical Association designates this enduring material for a maximum of  .50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ABIM MOC: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to .50 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

To receive CME credit and/or MOC points, you MUST complete the activity and the evaluation form. For ABIM MOC points, your information will be shared with the ABIM through the ACCME Program and Activity Reporting System (PARS). Please allow 6-8 weeks for your MOC points to appear on your ABIM records.

AAPA: AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of .50 hours of Category I credit for completing this activity.

AANPCP: The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

Healthcare Professionals

For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.  All healthcare professionals who are not MDs or DOs will receive a certificate of participation.

Instructions for Participation and Credit

To successfully earn credit, participants must complete the activity online during the valid credit period noted, following these steps:

  • Read the goals and objectives, accreditation information, and author disclosures.
  • View the educational video of the lecture.
  • Study the educational references.
  • Online, choose the best answer to each test question. Learners must receive a passing score of 80%.
  • Complete the activity evaluation and outcomes.

Upon successful completion of the test, evaluation and attestation, your certificate will be processed and emailed from within approximately 1 hour. Credits will be archived for 6 years; at any point within this time period you may login to your account to print a duplicate copy of your certificate.

Click the Disclosure Tab above for Faculty Information

Disclosure of Relevant Financial Relationships

As an organization accredited by the ACCME, Southern Medical Association requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner that could create a conflict of interest.

Southern Medical Association encourages Speakers/Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.

Kenneth Connell, MBBS DM (UWI), PhD (KCL), FACP, FRCP, FACC

Dr. Connell received his undergraduate and postgraduate training in medicine from the UWI St. Augustine & Cave Hill Campuses and graduated with MBBS and DM Internal Medicine degrees in 2000 and 2006, respectively. He was awarded a Barbados National Development Scholarship in 2007. He was awarded his Doctor of Philosophy degree on completion of studies from King's College London. He joined the Faculty of Medical Sciences as Lecturer in Clinical Pharmacology in 2011 and assumed duties of Deputy Dean - Phase 1 in August 2014 - August 2017.

Dr. Connell is currently chairman of the Barbados Ministry of Health & Wellness, Medical Council, with the main mandate of setting and maintaining the highest standards of health care delivery by medical practitioners. As a Clinical Pharmacologist, he also chairs the Barbados Drug Formulary Committee, a government appointed committee to review, update and recommend changes to drugs available for use in Barbados. Dr. Connell is currently President of the Heart & Stroke Foundation of Barbados from March 2017 - present. He is a member of the regional civil society organization, the Healthy Caribbean Coalition.

Dr. Connell is a Fellow of the American College of Physicians (ACP), the largest international college of doctors. He was elected as the youngest Governor of the ACP, as Governor of the ACP Caribbean Chapter, from 2016 to the present. He holds the prestigious distinction as a Fellow of the Royal College of Physicians UK (FRCP) and, for his contribution to hypertension and cardiovascular science, he was also awarded Fellowship of the American College of Cardiology (FACC).


  • Dr. Connell has no relevant financial relationships to disclose:
  • Dr. Connell does not intend to discuss off-label or investigational uses of drugs, mechanical devices, biologics, or diagnostics not yet approved by the FDA for use in the United States.

Planning Committee
The following planning committee members have no relevant financial relationships to declare:
Donald DiPette, MD
Christopher Morris, MD
Randall E. Glick, BSB/PM MCP
Jennifer Price, MA, SMA CME Program Manager

Click the Disclosure Tab above for Faculty Information

Course Materials


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