Case Report

Early Recognition of Risk Factors for Persistent Effects of Vecuronium



ABSTRACT: Renal failure and hepatic failure are important risk factors for persistent effects of vecuronium. We report a case in which vecuronium therapy after cardiac arrest led to prolonged paralysis due to severe renal and hepatic dysfunction not apparent until after vecuronium therapy. Biochemical and electrophysiologic examinations confirmed that neuromuscular blockade due to accumulation of one active metabolite of vecuronium was the primary cause of the patient's paralysis. This case highlights the importance of recognizing progressive renal and hepatic dysfunction after cardiac arrest when contemplating treatment with vecuronium.

This content is limited to qualifying members.

Existing members, please login first.

If you have an existing account please login now to access this article or view your purchase options.

Purchase only this article ($15)

Create a free account, then purchase this article to download or access it online for 24 hours.

Purchase an SMJ online subscription ($75)

Create a free account, then purchase a subscription to get complete access to all articles for a full year.

Purchase a membership plan (fees vary)

Premium members can access all articles plus recieve many more benefits. View all membership plans and benefit packages.