Original Article

Interactions of Lidocaine with General Anesthetics

Authors: WILLIAM R. McWHIRTER, MD, EVAN L. FREDERICKSON, MD, JOHN E. STEINHAUS, MD, PhD

Abstract

This experimental study confirmed the belief that lidocaine has a direct depressive effect as well as an indirect stimulating effect upon the cardiovascular system. The addition of depressants to the central nervous system modifies the stimulating effect of lidocaine.

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References