Case Report

Successful Treatment of In-transit Metastases From Merkel's Cell Carcinoma With Isolated Hyperthermic Limb Perfusion

Authors: AKSHAY S. GUPTA BA, STEPHEN HEINZMAN MD, EDWARD A. LEVINE MD

Abstract

ABSTRACT: Merkel's cell carcinoma is an uncommon neuroendocrine cutaneous neoplasm. An unusual mode of dissemination of this tumor is the phenomenon of in-transit metastases. We report complete resolution of in-transit metastases from a Merkel's cell carcinoma in response to treatment with isolated hyperthermic limb perfusion with melphalan. Limb perfusion appears to be a promising modality for such lesions.

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