Review Article
Neurocysticercosis: A Neurosurgical Perspective
Abstract
Neurocysticercosis (NCC) is the most common parasitic infection of the central nervous system (CNS) worldwide. An estimated 50 million people are infected and 50,000 people die annually as a result of this disease. 1 It accounts for 11% of hospital admissions and 35 to 45% of all neurosurgical procedures in certain endemic areas. 2 The incidence in the United States is increasing and involvement by neurosurgical services is increasing.This content is limited to qualifying members.
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References
1. Shandera WX, White AC Jr, Chen JC, et al. Neurocysticercosis in Houston, Texas: A report of 112 cases. Medicine (Baltimore) 1994; 73: 37–52.
2. Lombardo L, Mateos JH. Cerebral cysticercosis in Mexico. Neurology 1961; 11: 824–828.
3. Breeze R. Neurocysticercosis. Contemp Neurosurg 1990; 23: 1–5.
4. Garcia HH, Del Brutto OH. Taenia solium cysticercosis. Infect Dis Clin North Am 2000; 14: 97–119, ix.
5. Del Brutto OH, Noboa CA. Late onset epilepsy in Ecuador: Aetiology and clinical features in 225 patients. J Trop Geogr Neurol 1991; 1: 31–34.
6. Del Brutto OH, Santibanez R, Noboa CA, et al. Epilepsy due to neurocysticercosis: Analysis of 203 patients. Neurology 1992; 42: 389–392.
7. Del Brutto OH, Sotelo J, Roman GC. Neurocysticercosis: A Clinical Handbook. Exton, PA, Swets & Zeitliger, 1998.
8. Apuzzo MLJ, Dobkin WR, Zee CS, et al. Surgical considerations in treatment of intraventricular cysticercosis: An analysis of 45 cases. J Neurosurg 1984; 60: 400–407.
9. Bandres JC, White AC Jr, Samo T, et al. Extraparenchymal neurocysticercosis: Report of five cases and review of management. Clin Infect Dis 1992; 15: 799–811.
10. Cuetter AC, Garcia-Bobadilla J, Guerra LG, et al. Neurocysticercosis: Focus on intraventricular disease. Clin Infect Dis 1997; 24: 157–164.
11. Zee CS, Segall HD, Apuzzo MLJ, et al. Intraventricular cysticercal cysts: Further neuroradiologic observations and neurosurgical implications. AJNR Am J Neuroradiol 1984; 5: 727–730.
12. Del Brutto OH, Sotelo J. Albendazole therapy for subarachnoid and ventricular cysticercosis: Case report. J Neurosurg 1990; 72: 816–817.
13. Del Brutto OH, Sotelo J, Aguirre R, et al. Albendazole therapy for giant subarachnoid cysticerci. Arch Neurol 1992; 49: 535–538.
14. Noboa C. Albendazole therapy for giant subarachnoid cysticerci. Arch Neurol 1993; 50: 347–348(letter).
15. Sotelo J, Marin C. Hydrocephalus secondary to cysticercotic arachnoiditis: A long-term follow-up review of 92 cases. J Neurosurg 1987; 66: 686–689.
16. Espinoza B, Ruiz-Palacios G, Tovar A, et al. Characterization by enzyme-linked immunosorbent assay of the humoral immune response in patients with neurocysticercosis and its application in immunodiagnosis. J Clin Microbiol 1986; 24: 536–541.
17. Proano-Narvaez JV, Meza-Lucas A, Mata-Ruiz O, et al. Laboratory diagnosis of human neurocysticercosis: Double-blind comparison of enzyme-linked immunosorbent assay and electroimmunotransfer blot assay. J Clin Microbiol 2002; 40: 2115–2118.
18. Wilson M, Bryan RT, Fried JA, et al. Clinical evaluation of the cysticercosis enzyme-linked immunoelectrotransfer blot in patients with neurocysticercosis. J Infect Dis 1991; 164: 1007–1009.
19. Gekeler F, Eichenlaub S, Mendoza EG, et al. Sensitivity and specificity of ELISA and immunoblot for diagnosing neurocysticercosis. Eur J Clin Microbiol Infect Dis 2002; 21: 227–229.
20. Del Brutto OH, Rajshekhar V, White AC Jr, et al. Proposed diagnostic criteria for neurocysticercosis. Neurology 2001; 57: 177–183.
21. White AC Jr, Robinson P, Kuhn R. Taenia solium cysticercosis: Host-parasite interactions and the immune response. Chem Immunol 1997; 66: 209–230.
22. Pittella JE. Neurocysticercosis. Brain Pathol 1997; 7: 681–693.
23. White AC Jr, Shandera WX. Seizures and treatment for cerebral cysticercosis. N Engl J Med 1992; 327: 1955–1956(letter).
24. Dumas JL, Visy JM, Belin C, et al. Parenchymal neurocysticercosis: Follow-up and staging by MRI. Neuroradiology 1997; 39: 12–18.
25. Park SY, Barkovich AJ, Weintrub PS. Clinical implications of calcified lesions of neurocysticercosis. Pediatr Infect Dis J 2000; 19: 581–583.
26. Sheth TN, Pillon L, Keystone J, et al. Persistent MR contrast enhancement of calcified neurocysticercosis lesions. AJNR Am J Neuroradiol 1998; 19: 79–82.
27. Garcia HH, Evans CA, Nash TE, et al. Current consensus guidelines for treatment of neurocysticercosis. Clin Microbiol Rev 2002; 15: 747–756.
28. Bittencourt PR, Gracia CM, Martins R, et al. Phenytoin and carbamazepine decreased oral bioavailability of praziquantel. Neurology 1992; 42: 492–496.
29. Vazquez ML, Jung H, Sotelo J. Plasma levels of praziquantel decrease when dexamethasone is given simultaneously. Neurology 1987; 37: 1561–1562.
30. Baranwal AK, Singhi PD, Khandelwal N, et al. Albendazole therapy in children with focal seizures and single small enhancing computerized tomographic lesions: A randomized, placebo-controlled, double blind trial. Pediatr Infect Dis J 1998; 17: 696–700.
31. Carpio A, Santillan F, Leon P, et al. Is the course of neurocysticercosis modified by treatment with antihelminthic agents? Arch Intern Med 1995; 155: 1982–1988.
32. Padma MV, Behari M, Misra NK, et al. Albendazole in single CT ring lesions in epilepsy. Neurology 1994; 44: 1344–1346.
33. Singhi P, Ray M, Singhi S, et al. Clinical spectrum of 500 children with neurocysticercosis and response to albendazole therapy. J Child Neurol 2000; 15: 207–213.
34. Vazquez V, Sotelo J. The course of seizures after treatment for cerebral cysticercosis. N Engl J Med 1992; 327: 696–701.
35. Couldwell WT, Zee CS, Apuzzo MLJ. Definition of the role of contemporary surgical management in cisternal and parenchymatous cysticercosis cerebri. Neurosurgery 1991; 28: 231–237.
36. Martinez-Lopez M, Quiroz y Ferrari F. Cysticercosis. J Clin Neuroophthalmol 1985; 5: 127–143.
37. Ramina R, Hunhevicz SC. Cerebral cysticercosis presenting as mass lesion. Surg Neurol 1986; 25: 89–93.
38. Torrealba G, Del Villar S, Tagle P, et al. Cysticercosis of the central nervous system: Clinical and therapeutic considerations. J Neurol Neurosurg Psychiatry 1984; 47: 784–790.
39. Leblanc R, Knowles KF, Melanson D, et al. Neurocysticercosis: Surgical and medical management with praziquantel. Neurosurgery 1986; 18: 419–427.
40. Proano JV, Madrazo I, Avelar F, et al. Medical treatment for neurocysticercosis characterized by giant subarachnoid cysts. N Engl J Med 2001; 345: 879–885.
41. Colli BO, Martelli N, Assirati JA Jr, et al. Results of surgical treatment of neurocysticercosis in 69 cases. J Neurosurg 1986; 65: 309–315.
42. Madrazo I, Garcia-Renteria JA, Sandoval M, et al. Intraventricular cysticercosis. Neurosurgery 1983; 12: 148–152.
43. Proano JV, Madrazo I, Garcia L, et al. Albendazole and praziquantel treatment in neurocysticercosis of the fourth ventricle. J Neurosurg 1997; 87: 29–33.
44. Robles C, Chavarria M. A case of successfully treated cerebral cysticercosis [in Spanish]. Gac Med Mex 1980; 116: 65–71.
45. McCormick GF. Cysticercosis: Review of 230 patients. Bull Clin Neurosci 1985; 50: 76–101.
46. Sainte-Rose C, Hoffman HJ, Hirsch JF. Shunt failure, in Marlin AE (ed): Concepts in Pediatric Neurosurgery. Basel, S. Karger, 1989, vol 9, pp 7–20.
47. Kelley R, Duong DH, Locke GE. Characteristics of ventricular shunt malfunctions among patients with neurocysticercosis. Neurosurgery 2002; 50: 757–762.
48. Anandh B, Mohanty A, Sampath S, et al. Endoscopic approach to intraventricular cysticercal lesions. Minim Invasive Neurosurg 2001; 44: 194–196.
49. Bergsneider M. Endoscopic removal of cysticercal cysts within the fourth ventricle: Technical note. J Neurosurg 1999; 91: 340–345.
50. Bergsneider M, Holly LT, Lee JH, et al. Endoscopic management of cysticercal cysts within the lateral and third ventricles. J Neurosurg 2000; 92: 14–23.
51. Cudlip SA, Wilkins PR, Marsh HT. Endoscopic removal of a third ventricular cysticercal cyst. Br J Neurosurg 1998; 12: 452–454.
52. King JS, Hosobuchi Y. Cysticercus cyst of the lateral ventricle. Surg Neurol 1977; 7: 125–129.
