Editorial

Vitamin D Deficiency in Primary Hyperparathyroidism

Authors: Thomas Repas, DO, FACP, FACOI, FNLA, FACE, CDE

Abstract

Vitamin D deficiency is common in the general population, and even more prevalent in primary hyperparathyroidism. Boudou et al1 reported that 93% of patients who underwent parathyroidectomy had vitamin D deficiency compared to 38% of the general population. Another study found low vitamin D in 81% of patients with primary hyperparathyroidism (PTH) compared to 35% of healthy blood donors.2

This content is limited to qualifying members.

Existing members, please login first

If you have an existing account please login now to access this article or view purchase options.

Purchase only this article ($25)

Create a free account, then purchase this article to download or access it online for 24 hours.

Purchase an SMJ online subscription ($75)

Create a free account, then purchase a subscription to get complete access to all articles for a full year.

Purchase a membership plan (fees vary)

Premium members can access all articles plus recieve many more benefits. View all membership plans and benefit packages.

References

1. Boudou P, Ibrahim F, Cormier C, et al. A very high incidence of low 25 hydroxyvitamin D serum concentration in a French population of patients with primary hyperparathyroidism. J Endocrinol Invest 2006;29:511–515.
 
2. Moosgaard B, Vestergaard P, Heickendorff L, et al. Vitamin D status, seasonal variations, parathyroid adenoma weight and bone mineral density in primary hyperparathyroidism. Clin Endocrinol (Oxf) 2005;63:506–513.
 
3. Eastell R, Arnold A, Brandi ML, et al. Diagnosis of primary hyperparathyroidism: proceedings of the Third International Workshop. J Clin Endocrinol Metab 2009;94:340–350.
 
4. Stewart ZA, Blackford A, Somervell H, et al. 25-hydroxyvitamin D deficiency is a risk factor for symptoms of postoperative hypocalcemia and secondary hyperparathyroidism after minimally invasive parathyroidectomy. Surgery 2005;138:1018–1025; discussion 1025–1026.
 
5. Mikhail N. Clinical significance of vitamin D deficiency in primary hyperparathyroidism and safety of vitamin D therapy. South Med J 2011;104:29–33.
 
6. Binkley N, Krueger D, Gemar D, et al. Correlation among 25-hydroxy-vitamin D assays. J Clin Endocrinol Metab 2008;93:1804–1808.