Case Report

A Lady with Rapid Onset of Swollen Parotid Glands

Authors: Kai Ming Chow, MRCP, Ka Tak Wong, FRCR, Cheuk Chun Szeto, MRCP, MD

Abstract

Iodide mumps can occur after administration of any iodinated contrast media, irrespective of the osmolality of the contrast preparation. This condition is characterized by acute salivary gland swelling shortly after contrast study, presumably secondary to toxic accumulation of iodide in salivary glands with high iodide concentration. In this article, a case of iodide mumps is presented, along with a discussion of vulnerability due to renal impairment, which causes prolongation of the half-life of contrast media. A total of 30 additional cases of iodide mumps published in the English literature were reviewed. Despite the clinical observations that iodide mumps resolved with conservative management, it should be emphasized that recurrence is common if vulnerable patients are subjected to further iodinated contrast media.


Key Points


* Iodide mumps, swelling of the submandibular, sublingual, and parotid salivary glands, can occur after iodinated contrast media administration.


* Although the majority of patients have been described to resolve without intervention, the condition of iodide mumps has a high likelihood of recurrence if the same individual is exposed to iodinated contrast media again.


* Renal failure seems to be a risk factor for this adverse reaction, whereas low-osmolality contrast material might not eliminate the risk of iodide mumps.

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