Letter to the Editor

Adult T-cell Lymphoma with HTLV-I and HTLV-II Infection

Authors: Ramachandran Venkitaraman, MD, DM, FRCR, Tenali G. Sagar, MD, DM, Mathew K. George, MD, DM

Abstract

To the Editor:


Human T-cell lymphotrophic viruses (HTLV), retroviruses classified as HTLV-I and HTLV-II, predominantly infect CD4 and CD8 T-cells respectively. HTLV-I causes adult T-cell leukemia/lymphoma (ATL), while the relation of HTLV-II to causation of ATL is unclear.1 We present the case of a 48-year-old male patient with cutaneous lymphoma of T-cell origin and paraparesis, who was found to be infected with HTLV-I and HTLV-II.

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