Invited Commentary

Commentary on “Intravenous Thrombolysis Attenuates Neurologic Deterioration After Ischemic Stroke”

Authors: Michael G. Abraham, MD

Abstract

In the article “Intravenous Thrombolysis Attenuates Neurologic Deterioration After Ischemic Stroke,” Siegler and Martin-Schild attempt to determine the reduction of neurologic deterioration caused by stroke progression in acute stroke patients who received intravenous tissue plasminogen activator (IV tPA) compared with those who did not in their hospital cohort.1

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References

1. Siegler JE, Martin-Schild S. Intravenous thrombolysis attenuates neurologic deterioration after ischemic stroke. South Med J 2016;109:661-667.
 
2. Joo H, Wang G, George MG. Use of intravenous tissue plasminogen activator and hospital costs for patients with acute ischaemic stroke aged 18-64 years in the USA. http://svn.bmj.com/content/1/1/8. Published February 16, 2016. Accessed June 30, 2016.
 
3. Kleindorfer D, Lindsell CJ, Brass L, et al. National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate. Stroke 2008;39:924-928.
 
4. National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333:1581-1587.
 
5. American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Use of Intravenous tPA for Ischemic Stroke., Brown MD, Burton JH, et al. Clinical policy: use of intravenous tissue plasminogen activator for the management of acute ischemic stroke in the emergency department. Ann Emerg Med 2015;66:322-333. e31.