Invited Commentary

Commentary on “Advanced, Neglected Basal Cell Carcinoma”

Authors: Christian L. Stallworth, MD

Abstract

Basal cell carcinoma (BCC) accounts for approximately 80% of all skin cancers, with approximately 1 million new cases diagnosed annually. These tumors remain locally aggressive with exceedingly low metastatic potential (<0.01%), and cure is achieved in the majority of cases with excision and primary closure.1 Despite this, denial of illness is an established leading cause of delayed diagnosis and disease progression.2 What typically begins as an innocuous, small lesion can be neglected and follow an indolent growth pattern. Enlarged surface areas expectedly lead to larger resections and greater detriment to form and function. Reconstruction, in turn, becomes more complex and increases the risk of repair, time commitment by both patient and surgeon, and overall expense. In this issue of the Southern Medical Journal, Wiznia and colleagues highlight the importance of early detection to minimize the morbidity of this locally destructive disease process.3

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References

1. Bader RS. Basal cell carcinoma. http://www.emedicine.medscape.com/article/276624. Accessed February 12, 2014.
 
2. Alam M, Goldberg LH, Silapunt S, et al. Delayed treatment and continued growth of nonmelanoma skin cancer. J Am Acad Dermatol 2011;64:839-848.
 
3. Wiznia LE, Shanley KM, Federman DG. Advanced, neglected basal cell carcinoma. South Med J 2014;107:242-245.
 
4. Simmons S. Patient Education Series: Nonmelanoma skin cancers.Nursing 2012;42:39.
 
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7. Skin Cancer Foundation. Basal cell carcinoma (BCC). http://www.skincancer.org/skin-cancer-information/basal-cell-carcinom. Accessed February 12, 2014.
 
8. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: basal cell and squamous cell skin cancers. Version 2.2013. www.nccn.org. Accessed February 12, 2014.
 
9. Christenson LJ, Borrowman TA, Vachon CM, et al. Incidence of basal cell and squamous cell carcinomas in a population younger than 40 years. JAMA 2005;294:681-690.