Case Report

Ezetimibe-induced Acute Pancreatitis

Authors: Imran Ahmad, MD, Edward Ruby, MD, Harris Usman, MD, Mateen Hotiana, MD, Mehnaz Hussain, MD, Fahd Rahman, MD


Ezetimibe is a lipid-lowering agent that inhibits the intestinal absorption of cholesterol and other related phytosterols. It is used alone or in combination with other lipid-lowering agents in the treatment of various forms of hypercholesterolemia. Since its FDA approval in 2002, there are no known citations of ezetimibe-induced pancreatitis.

Key Points

* Drugs are an important, but rare, cause of acute pancreatitis.

* Ezetimibe, a lipid-lowering drug, can cause acute pancreatitis.

* Identification and discontinuation of the offending drug is of great importance in cases of drug-induced acute pancreatitis.

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