Ezetimibe is a lipid-lowering agent that inhibits the intestinal absorption of cholesterol and other related phytosterols. It is used alone or in combination with other lipid-lowering agents in the treatment of various forms of hypercholesterolemia. Since its FDA approval in 2002, there are no known citations of ezetimibe-induced pancreatitis.
* Drugs are an important, but rare, cause of acute pancreatitis.
* Ezetimibe, a lipid-lowering drug, can cause acute pancreatitis.
* Identification and discontinuation of the offending drug is of great importance in cases of drug-induced acute pancreatitis.
2. Venneman NG, Buskens E, Besselink MG, et al. Small gallstones are associated with increased risk of acute pancreatitis: potential benefits of prophylactic cholecystectomy? Am J Gastroenterol 2005;100:2540–2550.
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