Abstract

AbstractSickle cell anemia in pregnancy claims 10% to 20% of afflicted patients. With improved methods and availability of medical care the reproductive life span for these patients has increased markedly. With the above in mind, the pathology and rheodynamics of sickle red blood cells were reviewed and the relationship to blood viscosity presented. A detailed regimen of therapy is presented showing obtainable results in decreased oxygen tension by blood replacement technics. One must be aware of complications such as toxemia, hypoxic crisis, and congestive heart failure and measures taken to avoid sickle cell crisis. Oxygen tension should be monitored in order to quickly and adequately treat an impending crisis. Exchange transfusion technics are presented and their preventive and therapeutic value in sickle cell crisis and other associated complications is discussed.