Letter to the Editor
Multi-organ Failure Associated with Acute Parvovirus Infection and Exercise in a Patient with Sickle Beta Thalassemia
Abstract
Multi-organ failure is a rare and life-threatening complication of sickle cell anemia and sickle thalassemia.1–3 To our knowledge, this is the fourth reported case of multi-organ failure associated with sickle thalassemia.1 Patients present with abrupt, precipitous drops in hemoglobin and platelet counts, fever, and respiratory and liver failure.This content is limited to qualifying members.
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References
1. Tedla FM, Friedman EA. Multi-organ failure during a sickle cell crisis in sickle/beta thalassemia. Am J Kidney Dis 2003;42:1–4.
2. Hassel KL. Acute multi-organ failure syndrome: a potentially catastrophic complication of severe sickle cell pain episodes. Am J Med 1994;96:155–162.
3. Salzman S. Does splinting from thoracic bone ischemia and infarction contribute to the acute chest syndrome in sickle cell disease? Chest 2004;122:1–5.
4. Ahmed S, Siddiqui AK, Siddiqui RK, Kimpo M, Russo L, Mattana J. Acute pancreatitis during sickle cell vaso-occlusive painful crisis. Am J Hematol 2003;73:190–193.
