Case Report

Pregnancy Complicated by Guillain-Barré Syndrome

Authors: JEFFREY A. KULLER MD, VERN L. KATZ MD, M CATHLEEN McCOY MD, WENDY F. HANSEN MD

Abstract

ABSTRACT: We report a case of a pregnant patient with Guillain-Barré syndrome. Her symptoms, including weakness, vague numbness, urinary incontinence, and unsteady gait, were initially mild and mimicked many of the changes seen in pregnancy. Her progressive weakness was not preceded by any known illness. Evaluation of symptoms revealed an elevated cytomegalovirus IgM titer. When symptoms became severe, electromyography was done, showing a severe demyelinating motor-sensory neuropathy. After plasma exchange and vaginal delivery, symptoms resolved. Neither the patient nor her infant have had any long-term sequelae. Guillain-Barré syndrome may be difficult to diagnose in pregnancy but may be effectively treated with plasmapheresis.

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References