Letter to the Editor

Severe Eosinophilia during the Course of Toxic Shock Syndrome

Authors: Resat Ozaras, MD, Ali Mert, MD, Fehmi Tabak, MD, Muammer Bilir, MD, Recep Ozturk, MD


Staphylococcal toxic shock syndrome (STSS) is defined as the occurrence of fever, rash, hypotension, multiple organ dysfunction, and desquamation. 1 It is caused by toxigenic strains of Staphylococcus aureus. 2 The main hematologic changes are usually thrombocytopenia and leukocytosis with left shift. We described eosinophilia for the first time in 50% of 20 cases with STSS at our unit. 3

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1. Todd J, Fishaut M, Kapral F, Welch T. Toxic-shock syndrome associated with phage-group-I Staphylococci. Lancet 1978; 2: 1116–1118.
2. Davis JP, Chesney PJ, Wand PJ, LaVenture M. Toxic-shock syndrome: Epidemiologic features, recurrence, risk factors, and prevention. N Engl J Med 1980; 303: 1429–1435.
3. Mert A, Tabak F, Aktuglu Y. Eosinophilia in toxic shock syndrome: Review of 20 cases. Scand J Infect Dis 1998; 30: 320(letter).
4. Bernstein DI, Carney J, Cherry JD. Pseudo-toxic-shock syndrome due to a drug reaction. Clin Pediatr (Phila) 1983; 22: 524–525.