Original Article

Substance Abuse and Symptoms of Mental Illness Among HIV-positive Persons in the Southeast

Authors: Kathryn Whetten, PHD, Susan S. Reif, PHD, Sonia Napravnik, PHD, Marvin S. Swartz, MD, Nathan M. Thielman, MD, Joseph J. Eron, Jr, MD, Kristin Lowe, BS, Tomas Soto, PHD

Abstract

Objectives: Mental illness and substance abuse have been consistently associated with poor HIV-medication adherence and other negative health outcomes.


Methods: A brief mental health and substance use screening instrument was administered to 1,362 HIV-infected individuals receiving care at two academic medical center Infectious Diseases Clinics in North Carolina.


Results: Study results indicated high frequencies of symptoms of mental illness (60%), substance abuse (32%), and co-occurring symptoms of mental illness and substance abuse (23%). Younger age (P = 0.03), male sex (P < 0.001), and higher viral load (P < 0.001) were associated with substance use problems. White race (P = 0.001), younger age (P = 0.023), and higher viral load (P = 0.042) were associated with symptoms of mental illness.


Conclusions: In the Southeast, mental health and substance abuse services are sparse and stigma is high; thus, innovative treatment strategies are needed to address the high levels of co-occurring mental illness and substance abuse. Antiretroviral therapies will not reach their potential for slowing the HIV/AIDS epidemic and prolonging survival if comorbidities that influence patient behavior are not addressed.


Key Points


* Mental illness and substance abuse have been associated with poor HIV-medication adherence, which may result in treatment failure or poorer health outcomes.


* This study found a high prevalence of symptoms of mental health (60%) and substance abuse (32%) comorbidities in a population of HIV-positive patients receiving care in the Southeast.


* Such comorbidities should be addressed to improve HIV treatment outcomes.

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