Letter to the Editor
Thrombocytopenia Following 90Yttrium Glass Microsphere Liver Radioembolization
Abstract
To the Editor: We read with interest the article by Yang et al1describing a case of profound transient thrombocytopenia after 90Yttrium resin microsphere therapy for surgically unresectable hepatocellular carcinoma (HCC). We have also recently encountered this uncommon adverse sequella of liver radioembolization after 90Yttrium glass microsphere (TheraSphere®; MDS Nordion, Ottawa, Canada) administration, and present it herein.This content is limited to qualifying members.
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References
1. Yang CW, Yen HH, Su WW, et al. Profound transient thrombocytopenia associated with 90Yttrium microsphere therapy for inoperable hepatoma. South Med J 2010;103:1264-1268.
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4. Aster RH. Pooling of platelets in the spleen: role in the pathogenesis of "hypersplenic" thrombocytopenia. J Clin Invest 1966;45:645-657.
5. Fliedner TM, Friesecke I, Beyrer K. Medical Management of Radiation Accidents: Manual on the Acute Radiation Syndrome. London, The British Institute of Radiology, 2001.
