Primary Article

Transient Congenital Idiopathic Hypoparathyroidism



Two instances of transient congenital idiopathic hypoparathyroidism have been observed and considered with seven well documented cases in the literature. Hypocalcemic tetany develops after the first two days of life and persists despite dietary manipulation and calcium supplementation. Hyperphosphatemia is present. The chemical abnormality is readily corrected by parathyroid hormone injection and treated with vitamin D in pharmacologic doses together with calcium salts. After a few weeks or months treatment can be stopped without recurrence. No factors predisposing to delay in parathyroid maturation, such as low birth weight or maternal hypercalcemia, are present.

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