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Original Article

Community-Associated Methicillin-Resistant Staphylococcal Infection in an Inner City Hospital Pediatric Inpatient Population

Elizabeth Tejeda-Ramirez MD, Majda Behani MD, Robert J. Leggiadro MD
Volume: 102 Issue: 2 February, 2009

Abstract:

Background:Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a serious problem in the community setting, primarily as a cause of skin and soft tissue infections.Methods:A retrospective study based on the review of pediatric inpatients admitted to Lincoln Medical and Mental Health Center from March 2006 to February 2007 was performed.Results:Eighteen (55%) of the thirty-three patients identified were infected with community associated (CA) MRSA. All patients had skin and soft tissue infections. Seventeen (94%) of eighteen CA-MRSA isolates were susceptible to trimethoprim-sulfamethoxazole and tetracycline, respectively, and eleven (61%) were susceptible to levofloxacin.Conclusions:Skin and soft tissue infections are the most common clinical manifestation of CA-MRSA in our population. The 55% prevalence of MRSA in our patients suggests reconsidering empirical antimicrobial choices. Surgical intervention is important in the management of these infections, and clindamycin resistance among CA-MRSA isolates should be monitored locally to determine if empiric therapy is appropriate.

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References:

References1.Daum RS. Clinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. N Engl J Med 2007;357:380–390.DaumRSClinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus.N Engl J Med2007357380-3902.Klevens RM, Morrison MA, Fridkin SK, et al. Community-associated methicillin-resistant Staphylococcus aureus and healthcare risk factors. Emerg Infect Dis 2006;12:1991–1993.KlevensRM]]MorrisonMA]]FridkinSK&etal;Community-associated methicillin-resistant Staphylococcus aureus and healthcare risk factors.Emerg Infect Dis2006121991-19933.Crawford SE, Daum RS. Epidemic community-associated methicillin-resistant Staphylococcus aureus: modern times for an ancient pathogen. Pediatr Infect Dis J 2005;24:459–460.CrawfordSE]]DaumRSEpidemic community-associated methicillin-resistant Staphylococcus aureus: modern times for an ancient pathogen.Pediatr Infect Dis J200524459-4604.Fridkin SK, Hageman JC, Morrison M, et al. Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med 2005;352:1436–1444.FridkinSK]]HagemanJC]]MorrisonM&etal;Methicillin-resistant Staphylococcus aureus disease in three communities.N Engl J Med20053521436-14445.Kaplan SL. Treatment of community-associated methicillin-resistant Staphylococcus aureus infections. Pediatr Infect Dis J 2005;24:457–458.KaplanSLTreatment of community-associated methicillin-resistant Staphylococcus aureus infections.Pediatr Infect Dis J200524457-4586.Gorwitz RJ, Jernigan DB, Powers JH, et al. Participants in the CDC Convened Experts’ Meeting on Management of MRSA in the Community Strategies for Clinical Management of MRSA in the Community. Summary of an Experts’ Meeting Convened by the Centers for Disease Control and Prevention. 2006. Available at: http://www.cdc.gov/ncidod/dhqp/ar_mrsa_ca.html. Accessed September 4, 2008.7.Moran GJ, Krishnadasan A, Gorwitz RJ, et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med 2006;355:666–674.MoranGJ]]KrishnadasanA]]GorwitzRJ&etal;Methicillin-resistant S. aureus infections among patients in the emergency department.N Engl J Med2006355666-6748.Gorwitz RJ. A review of community-associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections. Pediatr Infect Dis J 2008;27:1–7.GorwitzRJA review of community-associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections.Pediatr Infect Dis J2008271-79.Lee MC, Rios AM, Aten MF, et al. Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant Staphylococcus aureus. Pediatr Infect Dis J 2004;23:123–127.LeeMC]]RiosAM]]AtenMF&etal;Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant Staphylococcus aureus.Pediatr Infect Dis J200423123-12710.Centers for Disease Control and Prevention. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997–1999. MMWR Morb Mortal Wkly Rep 1999;48:707–710.Centers for Disease Control and PreventionFour pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997–1999.MMWR Morb Mortal Wkly Rep199948707-71011.Centers for Disease Control and Prevention. Severe methicillin-resistant Staphylococcus aureus community-acquired pneumonia associated with influenza—Louisiana and Georgia, December 2006–January 2007. MMWR Morb Mortal Wkly Rep 2007;56:325–329.Centers for Disease Control and PreventionSevere methicillin-resistant Staphylococcus aureus community-acquired pneumonia associated with influenza—Louisiana and Georgia, December 2006–January 2007.MMWR Morb Mortal Wkly Rep200756325-329

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