Abstracts Archive - Southern Medical Association

Abstract | November 13, 2020

Salvage Chemotherapy with Mini-CVD + Inotuzumab Ozogamicin in a Patient with Relapsed Extramedullary BCR-ABL Negative B-cell Acute Lymphoblastic Leukemia

Isolated extramedullary ALL relapse is rare and represents a challenging clinical scenario as patients with extramedullary disease are often excluded from clinical trials and there is limited data regarding optimal treatment strategies. Inotuzumab ozogamicin is a targeted therapy approved for relapsed ALL, and two case reports suggest extramedullary disease may respond to inotuzumab alone.

Posted in: Medical Oncology9 Medicine & Medical Specialties21

Abstract | November 13, 2020

Obesity a Risk Factor for Severe COVID-19 Morbidity in Pediatric Population: A Case Series

With the emergence of COVID-19 pandemic, many studies have been published to determine the spectrum of illness, risk factors, prevention, and treatment strategies. Due to relatively fewer pediatric cases as compared to adults, there is a paucity of clinical data available to fully understand the risk factors and disease course in the pediatric population.

Posted in: Endocrinology, Diabetes, and Metabolism6 Infectious Disease8

Abstract | November 13, 2020

Mastocytic Enterocolitis in Systemic Mastocytosis: A Case Report

Systemic Mastocytosis, a subcategory of mastocytosis, has many different extracutaneous manifestations including gastrointestinal (GI) tract involvement. While GI involvement can be deemed nonspecific due to generalized mast cell mediators from the disease, a mastocytic enterocolitis has only been recently described and studied. This case presents a 65-year old male with a six-month history of chronic diarrhea as well as severe allergic reactions who was diagnosed with mastocytic enterocolitis after endoscopy. A trial therapy with omalizumab was successfully used as treatment for both the GI and systemic manifestations of mastocytosis.

Posted in: Bioethics & Medical Education5

Abstract | November 13, 2020

Assessing the efficacy of didactic modules in training health care professionals in interprofessional geriatrics care

The population of Americans aged 65 years or older will account for roughly 20% of the U.S. population by 2030. According to the National Council on Aging, roughly 80% of older adults have at least one chronic disease, such as hypertension, cardiovascular disease, and diabetes.

Posted in: Bioethics & Medical Education5

Abstract | November 13, 2020

Surveying the Opinions of Urology Program Directors Regarding the Change of USMLE Step 1 Scoring to Pass/Fail

Step 1 is an exam required of medical students as part of licensing which assesses knowledge and application of basic science concepts relating to medicine, and assigns students a numerical score, with 194 as the minimum to pass. Recently, the USMLE announced that Step 1 reports will change from a numerical grade to pass/fail.

Posted in: Bioethics & Medical Education5 Nephrology and Urology2

Abstract | November 13, 2020

Facilitators and Barriers associated with Mentoring Relationships from Medical Students’ Perspective – A Multi-Institutional Cross-Sectional Study

Mentoring is important for both professional and personal development in medical education. However, the characteristics of mentoring relationships among medical students are not well characterized. Despite its importance, the prevalence medical student mentorship ranges dramatically between 26%-77%, with studies primarily focusing on a specific population of medical students. The primary goal of this study was to update and determine the rate of mentorship among medical students across medical schools in the United States.

Posted in: Bioethics & Medical Education5

Abstract | November 13, 2020

Maternal Kratom use: A novel cause of Neonatal Abstinence Syndrome – A case series and literature review

Maternal opioid use is a well-known cause of neonatal abstinence syndrome (NAS). However, for treating opioid dependence several women have been identified to sought after non-opioid alternatives, especially during pregnancy, to avoid withdrawal symptoms in their newborns.

Posted in: Women’s & Children’s Health17

Abstract | November 13, 2020

Determining Trends and Factors associated with Self-Reported Physical Activity among Adolescents in Rural North Carolina

Insufficient physical activity (PA) in the youth can lead to adverse health outcomes, and youth in rural areas have particularly low PA. However, factors contributing to these levels remain unclear. Using data from a middle school-based wellness intervention called Motivating Adolescents with Technology to Choose HealthTM (MATCH), we evaluated demographic and environmental factors predicting PA in adolescents across rural North Carolina.

Posted in: Women’s & Children’s Health17

Abstract | November 13, 2020

A Rare Case of Familial Hypercholanemia

Sodium taurocholate cotransporting polypeptide (NTCP) is a carrier protein that is encoded by the gene SLC10A1. This protein is expressed in hepatocytes and functions to uptake bile acids from the plasma. Bile acids contribute to many metabolic and hormonal pathways. In the liver, bile acids are synthesized from cholesterol. The NTCP protein is exclusively expressed in the liver and plays an important role in the transport of conjugated bile acids from the portal blood into the liver.

Posted in: Women’s & Children’s Health17

Abstract | November 13, 2020

Understanding Attitudes Toward Contraception and Barriers to LARC Use in the Teenage Population

Long-acting reversible contraceptives (LARC), such as intrauterine devices (IUDs) and subdermal implants, are recommended as the first-line contraceptive for all women, including adolescents. Despite their high efficacy and safety, LARC use among sexually active teenagers remains under 6% nationally. Our study aimed to identify barriers to LARC use in adolescent patients at an urban pediatrics clinic in Eastern Virginia.

Posted in: Women’s & Children’s Health17

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