A Deadly Thrombotic Microangiopathy Syndrome without Schistocytosis

Authors: Biplab K. Saha, MD


Establishing a diagnosis of thrombotic microangiopathy (TMA) is not always straightforward, and significant vigilance and a low threshold of suspicion are necessary on the part of the clinician. A delayed or misdiagnosis may result in patient harm in the form of organ failure or even death. TMA is clinically diagnosed by the presence of microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and end-organ dysfunction.1
Posted in: Hematology10

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