Letter to the Editor

A Case of Nonoliguric Acute Kidney Injury Associated with Acetaminophen Overdose

Authors: Keiko Asao, MD, MPH, PhD, Ryan Gonzales, MD, Prasanna Isaac, MD, Bharat Sachdeva, MD, Kenneth Abreo, MD

Abstract

To the Editor:


Acetaminophen (N-Acetyl-p-aminophenol) poisoning is known to cause necrotic liver failure and occasionally result in extrahepatic toxicities, including nephrotoxicity. We report a case of a 32-year-old African-American man, in which nonoliguric acute kidney injury was associated with fulminant liver damage, following an intentional overdose of 48 grams (599 mg/kg) of acetaminophen and 2.4 grams (30 mg/kg) of diphenhydramine along with alcohol.

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References

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