Case Report

Anticonvulsant Hypersensitivity Syndrome: Treatment with Corticosteroids and Intravenous Immunoglobulin

Authors: Jenester Mostella, PHARMD, Robert Pieroni, MD, Richard Jones, MD, Christopher K. Finch, PHARMD

Abstract

We describe the case of a patient in whom anticonvulsant hypersensitivity syndrome developed during treatment with phenytoin and progressed when therapy was changed to phenobarbital. Although therapeutic options remain controversial, corticosteroids and IV immunoglobulin were used in our patient. The patient had a complete recovery, suggesting the potential benefit of corticosteroids and IV immunoglobulin for anticonvulsant hypersensitivity syndrome.

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