Original Article
Association of Cardiac Disease and Alcohol Use with the Development of Severe Ciguatera
Abstract
Objectives: Ciguatera is a foodborne illness that causes severe gastrointestinal and neurologic symptoms, but the risk factors for illness are not well established.Methods: In St Thomas, US Virgin Islands, we performed a case-control study for ciguatera, enrolling 47 patients primarily through the emergency department and 141 age- and sex-matched controls identified through an island-wide survey. We used conditional logistic regression to assess health-related risk factors for ciguatera, including comorbidities and alcohol and tobacco use.
Results: Cases were more likely than controls to report alcohol consumption at least weekly (odds ratio 5.7, 95% confidence interval 2.7–24.8). Cases also more frequently had a history of heart disease (odds ratio 6.3, 95% confidence interval 1.2–32.7). Previous ciguatera episodes, lower levels of education, and frequent fish consumption also were associated with illness.
Conclusions: This study provides preliminary evidence that preexisting health status influences an individual’s risk of developing severe ciguatera. There may be a benefit to educating high-risk individuals about preventing ciguatera.
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