Letter to the Editor

Burst of Autoimmunity with the Emergence of Primary Sjogren Syndrome, Cholestatic Autoimmune Hepatitis and Latent Autoimmune Diabetes of Adults (LADA)

Authors: Orhan Kocaman, MD, Cem Aygun, MD, Yesim Gurbuz, MD, Ayse Cefle, MD, Tolga Konduk, MD, Omer Senturk, MD, Altay Celebi, MD, Sadettin Hulagu, MD

Abstract

To the Editor:Primary Sjogren syndrome (pSS) is a systemic autoimmune disorder characterized by the simultaneous presence of keratoconjunctivitis sicca and xerostomia in the absence of other connective tissue diseases. Although pSS is an autoimmune exocrinopathy, the involvement of nonexocrine organs, such as the liver, kidneys and lungs, has been reported. Autoimmune hepatitis (AIH) and primary biliary cirrhosis are the most common liver diseases coinciding with pSS.1 Cholestasis is a rare finding in AIH. Latent autoimmune diabetes in adults (LADA) is the type of diabetes in adults which is initially noninsulin requiring but with immune markers of Type 1 diabetes that often progress to insulin dependence.2 We report a patient who presented with the symptoms and findings of pSS, cholestatic AIH and LADA at the same time.

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References

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