Letter to the Editor
Burst of Autoimmunity with the Emergence of Primary Sjogren Syndrome, Cholestatic Autoimmune Hepatitis and Latent Autoimmune Diabetes of Adults (LADA)
Abstract
To the Editor:Primary Sjogren syndrome (pSS) is a systemic autoimmune disorder characterized by the simultaneous presence of keratoconjunctivitis sicca and xerostomia in the absence of other connective tissue diseases. Although pSS is an autoimmune exocrinopathy, the involvement of nonexocrine organs, such as the liver, kidneys and lungs, has been reported. Autoimmune hepatitis (AIH) and primary biliary cirrhosis are the most common liver diseases coinciding with pSS.1 Cholestasis is a rare finding in AIH. Latent autoimmune diabetes in adults (LADA) is the type of diabetes in adults which is initially noninsulin requiring but with immune markers of Type 1 diabetes that often progress to insulin dependence.2 We report a patient who presented with the symptoms and findings of pSS, cholestatic AIH and LADA at the same time.This content is limited to qualifying members.
Existing members, please login first
If you have an existing account please login now to access this article or view purchase options.
Purchase only this article ($25)
Create a free account, then purchase this article to download or access it online for 24 hours.
Purchase an SMJ online subscription ($75)
Create a free account, then purchase a subscription to get complete access to all articles for a full year.
Purchase a membership plan (fees vary)
Premium members can access all articles plus recieve many more benefits. View all membership plans and benefit packages.