Case Report

Cholesterol Emboli-induced Renal Failure and Gastric Ulcer After Thrombolytic Therapy

Authors: Wassim A. Hitti, MD, John Anderson, MD

Abstract

Cholesterol embolization syndrome is a rare but devastating complication of thrombolysis. Clinical presentations are variable, which has resulted in labeling this syndrome as the great masquerader. Almost every organ in the body may be affected, but the syndrome commonly involves the kidney, skin, central nervous system, and gastrointestinal tract. Treatment is mainly supportive, with an emphasis on reducing the risk of recurrence. The case presented is a unique one of thrombolytic-induced cholesterol embolization syndrome causing renal failure, in which the diagnosis was supported by a biopsy of a gastric ulcer.


Key Points


* Thrombolytic-induced cholesterol embolization syndrome has been rarely reported.


* Cholesterol embolization syndrome may affect every organ.


* A definite diagnosis depends on documenting cholesterol clefts in affected organs.


* Treatment is mainly supportive.

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