Review Article

Common Misconceptions, Advancements, and Updates in Pediatric Vaccination Administration

Authors: Benjamin J. Oldfield, MD, Rosalyn W. Stewart, MD, MS

Abstract

Vaccines are among the greatest achievements in biomedicine and public health. Yet for a variety of reasons, some vaccinepreventable illnesses have experienced resurgences during the last decade. As such, there is a particular need for pediatric providers to be aware of the newest guidelines for vaccination administration to provide consistent and evidence-based recommendations and thoughtful reassurance to families. We aimed to enhance providers’ understanding of pediatric vaccinations by highlighting recent changes in vaccination guidelines and addressing common knowledge gaps. This is not a comprehensive list or systematic review of vaccination recommendations. Rather, we present a collection of new developments and misconceptions we have found particularly relevant in our own experience in providing vaccination education at a training institution.

This content is limited to qualifying members.

Existing members, please login first

If you have an existing account please login now to access this article or view purchase options.

Purchase only this article ($25)

Create a free account, then purchase this article to download or access it online for 24 hours.

Purchase an SMJ online subscription ($75)

Create a free account, then purchase a subscription to get complete access to all articles for a full year.

Purchase a membership plan (fees vary)

Premium members can access all articles plus recieve many more benefits. View all membership plans and benefit packages.

References

1. Roush SW, Murphy TV. Vaccine-Preventable Disease Table Working Group. Historical comparisons of morbidity and mortality for vaccine-preventable diseases in the United States. JAMA 2007;298:2155-2163.
 
2. Stewart RW. The importance of measles vaccinations. South Med J 2009; 102:236.
 
3. Centers for Disease Control and Prevention. Measles cases and outbreaks. www.cdc.gov/measles/cases-outbreaks.html. Accessed July 25, 2015.
 
4. Clemmons NS, Gastanaduy PA, Fiebelkorn AP, et al. MeaslesVUnited States, January 4-April 2, 2015. MMWR Morb Mortal Wkly Rep 2015;64:373-376.
 
5. Eskola J, Duclos P, Schuster M, et al. How to deal with vaccine hesitancy? Vaccine 2015;33:4215-4217.
 
6. Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases. Immunization schedules for 2015. http://redbook.solutions.aap.org/SS/Immunization_Schedules.aspx. Accessed July 25, 2015.
 
7. Centers for Disease Control and Prevention. Human papillomavirus vaccination coverage among adolescent girls, 2007-2012, and postlicensure vaccine safety monitoring, 2006Y2013VUnited States. MMWR Morb Mortal Wkly Rep 2013;62:591-595.
 
8. Hamborsky J, Kroger A, Wolfe S, eds. Epidemiology and Prevention of Vaccine-Preventable Diseases. 13th ed. Washington, DC: Public Health Foundation; 2015.
 
9. King GE, Hadler SC. Simultaneous administration of childhood vaccines: an important public health policy that is safe and efficacious. Pediatr Infect Dis J 1994;13:394-407.
 
10. Epidemiology and Prevention of Vaccine-Preventable Diseases. Hamborsky J, Kroger A, Wolfe S, eds. 13th ed. Washington, DC: Public Health Foundation; 2015:119-134.
 
11. Skoff TH, Kenyon C, Cocoros N, et al. Sources of infant pertussis infection in the United States. Pediatrics 2015;136:635-641.
 
12. Fiks AG, Hunter KF, Localio AR, et al. Impact of immunization at sick visits on well-child care. Pediatrics 2008;121:898-905.
 
13. Robison SG. Sick-visit immunizations and delayed well-baby visits. Pediatrics 2013;132:44-48.
 
14. Robison SG, Kurosky SK, Young CM, et al. Immunization milestones: a more comprehensive picture of age-appropriate vaccination. J Biomed Biotechnol 2010;2010:916525.
 
15. Muranjan M, Mehta C, Pakhare A. An observational, health service based survey for missed opportunities for immunization. Indian Pediatr 2011;48:633-636.
 
16. National Center for Immunization and Respiratory Diseases. General recommendations on immunization--recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2011;60:1-64.
 
17. Prevention of pneumococcal disease: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 1997;46(RR-8):1-24.
 
18. Cohn AC, MacNeil JR, Clark TA, et al. Prevention and control of meningococcal disease: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2013;62(RR-2):1-28.
 
19. Haemophilus b conjugate vaccines for prevention of Haemophilus influenzae type b disease among infants and children two months of age and older. Recommendations of the immunization practices advisory committee (ACIP). MMWR Recomm Rep 1991;40(RR-1):1-7.
 
20. Broder KR, Cortese MM, Iskander JK, et al. Preventing tetanus, diphtheria, and pertussis among adolescents: use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccines recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2006;55(RR-3):1-34.
 
21. Cassidy WM, Jones G, Williams K, et al. Safety and immunogenicity of concomitant versus nonconcomitant administration of hepatitis B, tetanus-diphtheria, and measles-mumps-rubella vaccines in healthy eleven- to twelve-year-olds. J Adolesc Health 2005;3:187-192.
 
22. Middleman AB, Bruner A. Tetanus, diphtheria, and acellular pertussis vaccine: a position statement of the Society for Adolescent Medicine. J Adolesc Health 2009;45:316-317.
 
23. Markowitz LE, Dunne EF, Saraiya M, et al. Human papillomavirus vaccination: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2014;63(RR-05):1-30.
 
24. Petrosky E, Bocchini JA Jr, Hariri S, et al. Use of 9-valent human papillomavirus (HPV) vaccine: updated HPV vaccination recommendations of the advisory committee on immunization practices. MMWR Morb Mortal Wkly Rep 2015;64:300-304.
 
25. Prymula R, Siegrist CA, Chlibek R, et al. Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials. Lancet 2009;374:1339-1350.
 
26. Stapleton FB. Prophylactic acetaminophen blunts immunogenicity of childhood vaccinations. New Engl J Med J Watch 2009;8:89.
 
27. American Academy of Pediatrics. Prophylactic acetaminophen may blunt immune response to vaccines. AAP Grand Rounds 2010;23:2.
 
28. Salmon DA, Dudley MZ, Glanz JM, et al. Vaccine hesitancy: causes, consequences, and a call to action. Am J Prev Med 2015;49(6 Suppl 4):S391-S398.