Letter to the Editor

Complete Resolution of Fibrosing Mediastinitis with Corticosteroid Therapy

Authors: Chitra Lal, MD, Darryl Weiman, MD, Mahmoud Eltorky, MD, PhD, Muthiah Pugazhenthi, MD

Abstract

Fibrosing mediastinitis, also known as sclerosing mediastinitis or mediastinal fibrosis, is characterized by an excessive fibrotic reaction in the mediastinum, which can produce compromise of the trachea, great vessels and other mediastinal structures.1There is no effective medical therapy known for this disease. We present a case of fibrosing mediastinitis, which resolved completely with corticosteroids.

This content is limited to qualifying members.

Existing members, please login first

If you have an existing account please login now to access this article or view purchase options.

Purchase only this article ($25)

Create a free account, then purchase this article to download or access it online for 24 hours.

Purchase an SMJ online subscription ($75)

Create a free account, then purchase a subscription to get complete access to all articles for a full year.

Purchase a membership plan (fees vary)

Premium members can access all articles plus recieve many more benefits. View all membership plans and benefit packages.

References

1.Goodwin RA, Nickell JA, Des Prez RM. Mediastinal fibrosis complicating healed primaryhistoplasmosis and tuberculosis. Medicine(Baltimore) 1972;51:227.
 
2.Minami S, Asai M, Iwahori K, et al. A case of fibrosing mediastinitis manifesting recurrent laryngeal nerve palsy. Nihon Kokyuki Gakkai Zasshi 2002;40:583–587.
 
3.Cordasco EM Jr, Ahmad M, Mehta A, et al. The effects of steroid therapy on pulmonary hypertension secondary to fibrosing mediastinitis. Cleve Clin J Med 1990;57:647–652.
 
4.Savelli BA, Parshley M, Morganroth ML. et al. Successful treatment of sclerosing cervicitis and fibrosing mediastinitis with tamoxifen. Chest 1997;111:1137–1140.
 
5.Urschel HC, Razzud MA, Netto GJ, et al. Sclerosing mediastinitis: improved management with histoplasmosis titer ketoconazole. Ann Thorac Surg 1990;50:215.