Case Report

Hypercalcemia and T-Cell Lymphoma With Acquired Immunodeficiency Syndrome: Occurrence Without Human T-Cell Leukemia Virus-I

Authors: SHYAM KOTTILIL, MD, PhD, ROBERT FRAM, MD, KAROLL CORTEZ, MD, STANLEY SCHWARTZ, MD, SREE HARI KESAN, MD

Abstract

We describe the case of a patient with acquired immunodeficiency syndrome (AIDS) who had a CD4 cell count of 60/&mgr;L, bilateral hilar adenopathy, and hypercalcemia. Transbronchial biopsy showed T-cell anaplastic large cell lymphoma. Serology was negative for human T-cell leukemia virus-I (HTLV-I). This appears to be the first case of T-cell anaplastic large cell lymphoma occurring in an AIDS patient with hypercalcemia who was seronegative for HTLV-I.

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