Editorial
If It Isn't Something, It's Something Else ...
Abstract
Disseminated disease due to nontuberculous mycobacteria (NTM) is among the most severe infections in persons with advanced HIV infection. The overwhelming majority (>90%) of these infections are caused by Mycobacterium avium complex (MAC).1–6 Disseminated disease due to MAC occurs only in persons who are severely immunocompromised with an average CD4+ T-cell count at presentation less than 25 cells/μL.3,4 Untreated, disseminated MAC is associated with very high mortality. In one study from the preantiretroviral era, only 13% of AIDS patients diagnosed with disseminated MAC survived one year without treatment.7This content is limited to qualifying members.
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