Case Report

Localized Bullous Pemphigoid in a Patient With B‐Cell Lymphoma

Authors: CONLETH A. EGAN MB, MRCPI, SCOTT R. FLORELL MD, JOHN J. ZONE MD

Abstract

ABSTRACTBullous pemphigoid (BP) is an immunobullous disease characterized by circulating IgG antibodies directed towards cutaneous basement zone antigens. We report the case of a patient who had BP localized to a stoma site. At initial examination, a nodule was noted on the temple, which proved to be a large cell lymphoma, B-cell phenotype. On Western immunoblot, the patient's serum showed circulating IgG antibodies reactive with the 230 kDa BP antigen and the 97 kDa linear IgA bullous dermatosis antigen. The co-incident onset of the two diseases suggest that this may represent a case of paraneoplastic BP.

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References