Article

Metamizole Use Among Hispanics in Miami: Report of a Survey Conducted in a Primary Care Setting

Authors: Santiago Garcia, MD; Mariana Canoniero, MD; Gilbert Lopes, MD; Andrés Omar Soriano, MD

Abstract

Background: Metamizole (dipyrone) is a myelotoxic, nonsteroidal anti-inflammatory agent that has been banned from the US market since 1979. However, dipyrone may be purchased in some areas of the US. We conducted a survey in a primary care setting in Miami, Florida to determine the prevalence of metamizole possession and use among Hispanics living in this area.


Methods: Participants consisted of 137 Hispanic outpatients interviewed consecutively during a primary care visit in the month of February 2005.


Results: Metamizole was possessed by 28% of the surveyed population. The most common reasons for using dipyrone were pain (72%) and fever (24%). The vast majority of patients had purchased the medication in Latin America (95%), in most instances without a prescription (95%). Nineteen patients (13%) had used the medication during the previous year.


Conclusions: Metamizole is available to Latino immigrants who reside in the US, despite the FDA ban imposed in 1977.


Key Points


* Since metamizole was banned by the Federal Drug Administration in 1977, most US physicians are not aware of the existence of this drug and its potential complications.


* Metamizole can be found in up to one third of Latino households.


* One third of patients reported having used the drug in the last year.


* The mortality rate associated with an episode of metamizole-induced agranulocytosis ranges from 7 to 32%.


* Physicians and public health authorities must promote safer alternatives to metamizole.

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